All articles about Application Area

Application Area

3 Examples of FDA approved AAVs in gene therapy

In this blog post, we'll show examples of AAVs as gene therapy vectors and examine the tangible results of FDA-approved AAV gene therapies, which offer actual solutions and hope for patients affected by genetic disorders. 

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Michael Mühlegger

September 19, 2023

Application Area

What is the difference between adeno-associated virus and adenovirus?

The main difference between adeno-associated viral vectors (AAV) and adenoviral vectors (AVV) is their genetic makeup. AAV is composed of a single-stranded DNA viral vector, while adenoviral vectors consist of double-stranded DNA.

michael-muehlegger

Michael Mühlegger

September 19, 2023

Application Area

Types of viral vectors

Various types of viral vectors are central to genetic research and medical advancements. These small carriers, obtained from various viruses, play an essential role in gene therapy and beyond. In this exploration, we will examine different types, the applications, unique attributes, and the complex terrain of producing viral vectors.

michael-muehlegger

Michael Mühlegger

September 19, 2023

Application Area

Adeno-Associated Virus (AAV) for gene therapy

The adeno-associated virus (AAV) is a very popular viral vector with great potential available for gene delivery. This article explores AAV vectors, their role in gene therapy, and their associated advantages and disadvantages.

Khalil Essani - Single Use Support

Khalil Essani

September 18, 2023

Application Area

Plasmid DNA manufacturing companies – market overview

In this article, we will give an overview of the pDNA manufacturing market – not only taking a look at the dry figures, but also highlighting the services that are offered by important plasmid DNA manufacturing companies.

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Daniel Tischler

September 13, 2023

Application Area

What is the function of plasmid DNA?

Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.

michael-muehlegger

Michael Mühlegger

September 13, 2023

Application Area

Plasmid DNA manufacturing: The process simply explained

The pDNA manufacturing process is multifaceted yet essential in the biopharmaceutical industry. Here, we will describe the process step by step.

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Michael Mühlegger

September 12, 2023

Application Area

What is a plasmid?

Plasmids are part of the genetic material in bacteria, complementing chromosomal DNA with additional functions. But there is much more to plasmids, as you can read in this article.

michael-muehlegger

Michael Mühlegger

September 7, 2023

Application Area

Plasmid DNA – 7 facts about pDNA

Plasmid DNA is not only found in bacteria, but also ubiquitous in biotechnology. In this article, we have collected 7 interesting facts on pDNA.

michael-muehlegger

Michael Mühlegger

September 7, 2023

Application Area

Revolutionizing Commercial Aliquotation in Advanced Therapies

Single Use Support unveils its latest customized innovation within the product range of automated of biopharmaceutical manufacturing, RoSS.FILL. With its unmatched precision and cutting-edge technology, RoSS.FILL CGT is a game-changer for the cell and gene therapy industry.

BRMO

Brian Moloney

August 22, 2023

Application Area

Cryopreservation techniques & best practice freezing methods

The preservation of cells at cryogenic temperature can be achieved using different techniques. This is far from a simple freezing process; it's a carefully controlled method that prevents the formation of ice crystals, thus maintaining the integrity of the biological material.

BRMO

Brian Moloney

August 11, 2023

Application Area

How to prepare cells for cryopreservation?

This guide provides an overview of the necessary steps and considerations for preparing cells for cryopreservation. Key topics include selecting appropriate cells, cultivating and harvesting them under controlled conditions, utilizing proper cryoprotective agents, and applying specific freezing techniques.

BRMO

Brian Moloney

August 11, 2023