All articles about Application Area
Application Area
How to measure and improve cell viability?
Cell viability is a fundamental parameter in cell-based biopharma processing and cell banking. Therefore, it is essential not only to measure cell viability, but also to take measures for its improvement. Learn more in this article.
Michael Eder
July 31, 2023
Application Area
What is the difference between cytotoxicity and cell viability?
Although there are significant differences between cytotoxicity and cell viability, they both are frequent concepts in cell biology and cell banking. We will discuss these two parameters in this article.
Michael Mühlegger
July 26, 2023
Application Area
What is cell viability and cell proliferation?
Both cell viability and cell proliferation are important parameters in cell banking. In this article, we will shed light on these two concepts.
Michael Eder
July 26, 2023
Application Area
What is mRNA?
mRNA is the acronym for messenger ribonucleic acid – but there is much more to know about this fascinating molecule, as it is essential in elementary biological processes. In this article, we will give readers a brief explanation of what mRNA actually is and discuss its application in medicine as well as recent advances in mRNA technology.
Michael Eder
July 6, 2023
Application Area
The function of mRNA
In order for the genetic information encoded by DNA to become an accessible blueprint for protein production, mRNA is indispensable. In this article, we will provide a comprehensive definition of mRNA and illustrate its main functions.
Michael Eder
July 6, 2023
Application Area
mRNA Manufacturing – The 5 process steps of mRNA production
mRNA is a fundamental component of several biological processes, and its unique properties are used in different fields of medicine and research. mRNA manufacturing, however, is a complicated endeavor. In this article, we will take a detailed look at mRNA manufacturing and the advantages that come with single-use technologies.
Daniel Tischler
July 5, 2023
Application Area
mRNA cold chain: considerations & solutions for safe handling
Meeting the temperature requirements of mRNA-based products is essential to maintain product efficiency and safety. Effective mRNA cold chain management is necessary, but comes with several challenges. In this article, we will discuss relevant considerations and innovative solutions in mRNA cold chain management.
Michael Eder
July 5, 2023
Application Area
Freezing mRNA: best practice
Considering the manifold applications of mRNA, it is essential to establish optimal freezing processes that maintain viability and effectiveness. In this article, we will compare different freezing methods for mRNA.
Alexander Fuchs
July 4, 2023
Application Area
Lipid nanoparticles: All you need to know about LNPs
After the first LNPs were approved by FDA in 2018, the whole field of LNPs as drug delivery systems has expanded rapidly. In the following article we will explore what qualifies lipid nanoparticles as one of the most promising pharmaceutical drug delivery systems and will take a closer look at their structure, applications and challenges connected with the manufacturing process.
Michael Mühlegger
June 30, 2023
Application Area
Filling, Filtering & Dispensing mRNA
As the demand for messenger RNA-based products continues to rise, efficient fluid management plays a crucial role in ensuring the high-quality production of mRNA drug products. This article is about challenges and the latest advancements in fluid management techniques, focusing on filling, filtering, and aliquoting mRNA during the manufacturing process.
Brian Moloney
June 29, 2023
Application Area
Filling & aliquoting LNPs in single-use bags
The use of lipid nanoparticles has gained significant attention due to their potential applications in drug delivery systems. In this article we explore the process of filling and aliquoting LNPs in single-use bags and highlight its significance and key considerations.
Brian Moloney
June 28, 2023
Application Area
Freezing LNPs & the impact on their long-term stability
Freezing is a significant process step in the manufacturing of LNP-based products. In this article, we will therefore take a look at the impact freezing has on lipid nanoparticles.
Alexander Fuchs
June 26, 2023
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