All articles about Freeze & Thaw

Freeze & Thaw

Freezing & Storing biopharmaceuticals at -80°C and below - The best economical choice

In this publication we show that the intital price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecylcle analysis they outpace conventional options regarding total costs.

Alexander Fuchs | Single Use Support

Alexander Fuchs

January 19, 2021

Freeze & Thaw

Efficient freezing and thawing of vaccines with single-use technologies

The global distribution of any medical substance requires more than what meets the eye. Before a vaccine can finally be shipped, it needs to be safely processed and contained. Single use technologies offer a number of advantages that cover the entire biopharmaceutical process, including development, manufacturing and logistics.

micheal-eder

Michael Eder

December 21, 2020

Freeze & Thaw

Now available: Freeze-thaw platform for rent

Test our RoSS.pFTU lab scale – the perfect freeze and thaw technology for single use bags that is completely standalone, meaning it is compatible with any established bag brand. You can rent our freeze-thaw platform for up to three months. You will be reimbursed for the rent paid if you choose to purchase the platform.

micheal-eder

Michael Eder

May 14, 2019

Freeze & Thaw

Storing and shipping frozen drug substances – why single-use systems are the optimal solution

Due to increased efficiency, flexibility and cost reduction, it has become standard practice to use integrated single use freeze-thaw systems with single use bags, tubing and connectors. Find out what the reasons for this are here!

micheal-eder

Michael Eder

January 18, 2019

Recommended Downloads

E-Book

Whitepaper: Scalable Freezing & Thawing of Pharmaceutical Bulk

The process of freezing can lead to a denaturation of the protein. In fact, parts of the protein solution will always show less activity based on the stress the protein is exposed to during freezing and thawing. It is therefore important to optimize the freezing and thawing process in order to minimize activity loss. A key parameter for this process is the freezing or thawing rate.

E-Book

Whitepaper: How Controlled & Scalable Freezing Becomes Reality

Scalability around freezing means the ability to guarantee constant freezing kinetics on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. This guide covers how to achieve scalable freezing & thawing of biopharmaceuticals by showing What is scalability? Setup for controlled icefront growth speed Scalability results Outcomes

E-Book

Study: Increased CHO Cell Viability with Controlled Liquid Nitrogen Freezer

The study was conducted aiming to optimize the cryogenic freezing process of the mammalian CHO-K1 cell line with an innovative controlled rate liquid nitrogen freezer (RoSS.LN2F). The study incorporated three viability assays to comprehensively assess the impact of varying freezing rates on post-thaw cell recovery | Trypan blue | LIVE/DEAD | Fluorescence.