All articles about Solution
Solution
CMO vs. CDMO: What are the differences?
Both CMOs and CDMOs are frequently relied on partners in the pharmaceutical industry. But what sets them apart, where are their strengths, and what do they offer?
Michael Mühlegger
March 12, 2024
Solution
Single-use bag manufacturers: the major players
The advanced platforms of the newest generation of single use bags are generally compatible with a variety of bag brands and volumes. One of these platforms is Single Use Support’s RoSS®, which offers the benefit of not only being bag agnostic but also highly flexible thanks to its modular design. Learn more about the biggest player in the industry!
Michael Eder
March 5, 2024
Solution
Stressing Cells: The Role of Cryoprotectants in ATMP Cryopreservation
The objective of an optimal cryopreservation strategy is to deactivate (put on hold) degenerative cellular pathways and preserve proliferative potential by reducing the temperature below –130°C. To reduce the effects of ice crystal and osmotic injuries, cryopreservation protocols usually incorporate cryoprotective agents (CPAs).
Khalil Essani
February 8, 2024
Solution
Aseptic filling machines for pharmaceutical liquids
Aseptic filling machines are widely adopted in the biopharma industry. From individual components and equipment to considerations like scalability – in this article, we will take a closer look at these systems.
Michael Eder
January 16, 2024
Solution
Aseptic filling & processing of biologics
Many drug products require aseptic conditions along their entire production process. In this article, we will discuss essential considerations on aseptic filling in the biopharma industry.
Michael Eder
January 16, 2024
Solution
Aseptic filling of large volumes of drug substances
Especially in large volume drug manufacturing, aseptic filling can be a challenging yet all the more important task to ensure product safety and effectiveness. In this article, we will discuss what manufacturers ought to be aware of.
Michael Eder
January 16, 2024
Solution
Increasing Patient Safety: Risk assessment for small volume fluid management
Autologous therapies and other ATMPs with small volumes exhibit certain specific requirements. The scope of handling advanced therapies require special handling and care. When handling of small volumes is already automated in an early stage, it is a way more straightforward path to commercialization of the drug product. The benefit of a closed systems with automated solutions add value by offering a higher degree of sterility, safety, and process flexibility.
Brian Moloney
December 4, 2023
Solution
Advancements in Small Volumes Drug Freezing Techniques
Freezing small volumes extends beyond laboratory settings to include commercialized manufacturing processes for small batches in biomanufacturing, like cell banking, gene therapies utilizing viral vectors, lipid nanoparticles, and fill & finish procedures.
Alexander Fuchs
November 20, 2023
Solution
Liquid handling in biopharma: Efficiency gains with automated systems
Liquid handling is one of the cornerstones in countless biopharmaceutical manufacturing processes. In this article, we will illustrate how automated systems can improve efficiency – along with several other aspects.
Michael Mühlegger
November 16, 2023
Solution
Bioprocess tubing – choosing the right option
Tubing solutions in the field of biopharmaceuticals encompass a wide range of applications, each with its own set of unique challenges and requirements. In this article, we will illustrate them in more detail.
Michael Eder
November 14, 2023
Solution
How to avoid single-use bag leakages in bioprocessing
Single-use bag leakage and the resulting product loss can cause delays in life-saving treatments, safety risks as well as financial loss. Therefore, this article will discuss aspects to consider in order to keep single-use bags safe and sound.
Michael Eder
November 14, 2023
Solution
Automated aliquoting system - for small & large volumes
Be it small volume or bulk filling – aliquoting is a necessary step in biopharma manufacturing at every scale. In this article, we will cover the topic of automated aliquoting systems like RoSS.FILL.
Michael Eder
November 14, 2023
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