All articles about Solution
Solution
Bioprocess solutions: Advancements with single-use technology
Bioprocess manufacturing has seen remarkable advancements through the utilization of single-use technology. This shift in process development brings numerous advantages – in this article, we will cover some major advances.
Michael Mühlegger
November 13, 2023
Solution
Fluid management systems: 7 considerations to be made
What are the necessary considerations when implementing automated fluid management systems in biopharma? In this article, we will discuss seven of the most important ones.
Michael Mühlegger
November 13, 2023
Solution
Fluid management in biopharma: Advantages of single-use systems
Major changes in biopharma industry require new approaches along the supply chain of most innovative biologics – including fluid management. Here's to discover how single-use products help to achieve considerable improvements.
Khalil Essani
November 7, 2023
Solution
Biopharmaceutical processing – how disposable solutions increase safety and efficiency
Biopharmaceutical processing is indispensable across various fields of medicine and life sciences. In this article, we will discover how single-use solutions can increase efficiency and safety in biopharmaceutical processing.
Khalil Essani
November 6, 2023
Solution
Sustainable Freezing in Biopharma: An Exploration of Natural Gas Usage
In the biopharmaceutical sector, the utilization of F-Gases is on a decline. However, the need for cryopreservation of drug substances will remain. In order to contribute to a more environmentally friendly freezing of drugs, more sustainable technologies need to be developed and applied. But is sustainable freezing even possible?
Alexander Fuchs
September 6, 2023
Solution
Cryopreservation techniques & best practice freezing methods
The preservation of cells at cryogenic temperature can be achieved using different techniques. This is far from a simple freezing process; it's a carefully controlled method that prevents the formation of ice crystals, thus maintaining the integrity of the biological material.
Brian Moloney
August 11, 2023
Solution
How to prepare cells for cryopreservation?
This guide provides an overview of the necessary steps and considerations for preparing cells for cryopreservation. Key topics include selecting appropriate cells, cultivating and harvesting them under controlled conditions, utilizing proper cryoprotective agents, and applying specific freezing techniques.
Brian Moloney
August 11, 2023
Solution
Thawing cells – process, difficulties & recommendations
Cell thawing is a critical procedure in the area of life science and medicine. Ensuring a gentle thawing of frozen cells is essential for preserving their viability and functionality. In this article, we will highlight the cell thawing process, discuss common challenges, and provide recommendations for achieving optimal results in cell banking.
Brian Moloney
August 9, 2023
Solution
Homogenization of cells & aliquotation in single-use bags
Who can relate to the situation when every cell aliquot is different? That's why cell homogenization and aliquotation are important requirements in modern cell biology research, relevant for scientists and laboratory staff. Scientists and process engineers benefit from uniform cell distribution throughout multiple single-use bioprocess containers for cell banking or other bioprocessing steps.
Brian Moloney
August 9, 2023
Solution
Cryovessels in Biopharmaceutical Manufacture: When Does the Tank Run Out?
It is many decades since cryovessels emerged as a groundbreaking solution in the biopharmaceutical industry, enabling the safe and efficient storage of bulk drug substances. However, the introduction of plate-based freezing methods has further advanced the technology available for the freezing of biopharmaceuticals, offering improved product quality and consistency.
Daniel Tischler
July 28, 2023
Solution
Lyophilization considerations: Comparing freeze-drying to freezing for biopharmaceutical products
Not all biopharmaceuticals are suitable for freeze-drying. Depending on the specific stability requirements the preservation of biopharmaceuticals is either with cryopreservation or lyophilization.
Michael Eder
July 28, 2023
Solution
Interview: Considerations for Sterilization of single-use assemblies
In an interview with single-use systems expert David Seifert, he compares sterilization methods and shares insights, benefits and outlooks in the field of single-use sterilization technology.
David Seifert
July 14, 2023
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