Knowledge

August 1, 2023

How to maintain a cell bank?

micheal-eder
Michael Eder

Proper storage of cells and maintenance of a cell bank is essential to uphold the integrity and reproducibility of experimental results. In this article, we will show best practices for maintaining a cell bank, from initial cell line characterization to cGMP compliance, storage, and troubleshooting tips.

August 1, 2023

Advantages of cell banking

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Michael Eder

By preserving and storing valuable cell lines, cell banking ensures a stable and consistent source of cells for various applications. In this blog post, we will explore the numerous advantages of cell banking and its pivotal role in driving advancements in the fields of science and medicine.

August 1, 2023

The purpose of cell banking: Uses & Applications

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Michael Eder

At the core of cutting-edge research and biopharmaceutical production lies the crucial need to preserve and store precious cell lines, ensuring their availability for future studies and therapeutic applications. In this article, we will explore the purpose and applications of cell banking, examining its significance in scientific discoveries and medical breakthroughs.

August 1, 2023

Cell banking: Definition, Process & Manufacturing

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Michael Eder

Cell banking plays a key role in securing valuable cell lines and biological resources for future research and applications in the field of biotechnology. This article aims to provide a comprehensive overview of cell banking, its definition, importance, and the essential components involved in establishing and maintaining cell banks.

August 1, 2023

Freezing cells – considerations and solutions

BRMO
Brian Moloney

A fundamental process to preserve the ex vivo viability of cells is freezing them to extremely low temperatures. This is a complex and delicate task, requiring both expertise and professional equipment. In this article, we will take a look at the most important aspects of the cell freezing process.

July 31, 2023

How to measure and improve cell viability?

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Michael Eder

Cell viability is a fundamental parameter in cell-based biopharma processing and cell banking. Therefore, it is essential not only to measure cell viability, but also to take measures for its improvement. Learn more in this article.

July 28, 2023

Cryovessels in Biopharmaceutical Manufacture: When Does the Tank Run Out?

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Daniel Tischler

It is many decades since cryovessels emerged as a groundbreaking solution in the biopharmaceutical industry, enabling the safe and efficient storage of bulk drug substances. However, the introduction of plate-based freezing methods has further advanced the technology available for the freezing of biopharmaceuticals, offering improved product quality and consistency.

July 28, 2023

Lyophilization considerations: Comparing freeze-drying to freezing for biopharmaceutical products

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Michael Eder

Not all biopharmaceuticals are suitable for freeze-drying. Depending on the specific stability requirements the preservation of biopharmaceuticals is either with cryopreservation or lyophilization.

July 26, 2023

What is the difference between cytotoxicity and cell viability?

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Michael Mühlegger

Although there are significant differences between cytotoxicity and cell viability, they both are frequent concepts in cell biology and cell banking. We will discuss these two parameters in this article.

July 26, 2023

What is cell viability and cell proliferation?

micheal-eder
Michael Eder

Both cell viability and cell proliferation are important parameters in cell banking. In this article, we will shed light on these two concepts.

July 14, 2023

Interview: Considerations for Sterilization of single-use assemblies

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David Seifert

In an interview with single-use systems expert David Seifert, he compares sterilization methods and shares insights, benefits and outlooks in the field of single-use sterilization technology.

July 6, 2023

What is mRNA?

micheal-eder
Michael Eder

mRNA is the acronym for messenger ribonucleic acid – but there is much more to know about this fascinating molecule, as it is essential in elementary biological processes. In this article, we will give readers a brief explanation of what mRNA actually is and discuss its application in medicine as well as recent advances in mRNA technology.